Game of Thrones' casting process led to some intriguing "almost-casting" scenarios. Iwan Rheon, who auditioned for Jon Snow, ended up as Ramsay Bolton, delivering a chilling performance. Alfie Allen, initially considered for Jon Snow, excelled as Theon Greyjoy. Joe Dempsie, not fitting Jon Snow, portrayed Gendry, proving to be a great fit. Carice Van Houten turned down Cersei Lannister due to scheduling conflicts but shone as Melisandre.

Natalie Dormer, who auditioned for Melisandre, found success as Margaery Tyrell. Conan Stevens, initially offered Khal Drogo, played Ser Gregor Clegane, while Jason Momoa's intense portrayal made Drogo iconic.

Liam Cunningham, initially rejected for a role, later became the beloved Davos Seaworth. Conleth Hill, missing out on King Robert Baratheon, excelled as Varys.

Eugene Simon, who auditioned for Joffrey Baratheon, brought depth to Lancel Lannister. The show's impeccable casting resulted in a talented and well-rounded ensemble, making it hard to imagine anyone else bringing these iconic characters to life.